Cohen Hubal EA, Reif DM, Slover R, Mullikin A, Little JC. Children's Environmental Health: A Systems Approach for Anticipating Impacts from Chemicals. Int J Environ Res Public Health. 2020 Nov 11;17(22):8337. doi: 10.3390/ijerph172…
Structural-based connectivity and omic phenotype evaluations (SCOPE): a cheminformatics toolbox for investigating lipidomic changes in complex systems
David presented a seminar as part of the Society of Toxicology (SOT) Risk Assessment Specialty Section (RASS) series. The slides and recording are available at:
https://www.toxicology.org/groups/ss/RASS/downloads.asp
The multi-dimensional embryonic zebrafish platform predicts flame retardant bioactivity. Truong L, Marvel S, Reif DM, Thomas D, Pande P, Dasgupta S, Simonich MT, Waters KM, Tanguay RL.Reprod Toxicol. 2020 Aug 19:S0890-6238(20)30196-9. doi: 10.1016/j.reprotox.2020.08.007. Online ahead of print.PMID:…
David Reif was promoted to full Professor by the Department of Biological Sciences.
Kyle Roell, Tammy Havener, David Reif*, John Jack, Howard McLeod, Tim Wiltshire, Alison Motsinger-Reif*
Front. Genet. | doi: 10.3389/fgene.2019.00829
Synergistic chemotherapy drug response is a genetic trait in lymphoblastoid cell lines
Lymphoblastoid cell lines (LCL) are a high…
Burnett SD, Blanchette AD, Grimm FA, House JS, Reif DM, Wright FA, Chiu WA, Rusyn I. Population-based toxicity screening in human induced pluripotent stem cell-derived cardiomyocytes. Toxicol Appl Pharmacol. 2019 Aug 16;381:114711. doi: 10.1016/j.taap.2019.114711. [Epub ahead of print] PubMed P…
Kosnik MB, Reif DM. Determination of chemical-disease risk values to prioritize connections between environmental factors, genetic variants, and human diseases. Toxicol Appl Pharmacol. 2019 Jul 16:114674. doi: 10.1016/j.taap.2019.114674. [Epub ahead of print] PubMed PMID: 31323264.
MB Kosnik, A Planchart, SW Marvel, DM Reif, CJ Mattingly (2019) Integration of curated and high-throughput screening data to elucidate environmental influences on disease pathways. Computational Toxicology, 100094
The Tanguay + Reif labs met in Oregon for their second joint retreat.
The retreat started with scientific sessions and lab tours at Oregon State University and the Sinnhuber Aquatic Research Lab (SARL) in Corvallis. We then moved to the Oregon Coast for more scientific sessions, hiking, and int…
The workshop, "Fish and amphibian embryos as alternative models in toxicology and teratology" was organized by the Helmholtz Centre for Environmental Research and hosted at L'Oréal headquarters in Paris, France.
Kimberly T. To, Rebecca C. Fry, David M. Reif. Characterizing the effects of missing data and evaluating imputation methods for chemical prioritization applications using ToxPi. BioData Mining. 2018.
https://rdcu.be/XYtJ
Scoping Plan to Assess the Hazards of Organohalogen Flame Retardants
https://www8.nationalacademies.org/cp/CommitteeView.aspx?key=49937
Mahapatra D, Franzosa JA, Roell K, Kuenemann MA, Houck KA, Reif DM, Fourches
D, Kullman SW. Confirmation of high-throughput screening data and novel
mechanistic insights into VDR-xenobiotic interactions by orthogonal assays. Sci
Rep. 2018 Jun 11;8(1):8883. doi: 10.1038/s41598-018-27055-3. PubMe…
Kyle Roell successfully defended his PhD, entitled "Statistical Methods for Assessing the Genetic Etiology of Synergistic Drug Interactions".
Dr. Kyle Roell is currently a postdoc with Stephanie Engel in the Department of Epidemiology at UNC Chapel Hill.
David Reif was a moderator and member of the planning committee for the National Academy of Sciences workshop "Informing Environmental Health Decisions Through Data Integration".
The workshop brought together thought leaders from diverse fields to explore the promise and potential pitfalls of e…
Balik-Meisner M, Truong L, Scholl EH, Tanguay RL, Reif DM. Population genetic diversity in zebrafish lines. Mamm Genome. 2018 Jan 24. doi: 10.1007/s00335-018-9735-x. [Epub ahead of print] PubMed PMID: 29368091.
https://www.ncbi.nlm.nih.gov/pubmed/29368091
A report on the SEAZIT (Systematic Evaluation of the Application of Zebrafish in Toxicology) Ontologies Workshop has been published:
https://ntp.niehs.nih.gov/iccvam/methods/dev-repro/ontologies-wksp-rept-2017.pdf